Compare top-rated male enhancement treatments, with research-backed effectiveness and expert reviews of product popularity.
Last Updated: December 2024
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Erectile dysfunction (ED), defined as difficulty in achieving or maintaining an erection, is a common experience for many men. In fact, research shows that about 40% of men under 40 have faced it, and nearly 70% by the age of 70.9
Thankfully, ED is an extensively studied condition, and there are numerous effective treatment options available.
At some point in their lives, nearly every man will experience symptoms of ED.5 It is not always a lifelong condition meaning symptoms can fluctuate, appearing occasionally or becoming more persistent over time.
The primary signs of ED include:
Getting an accurate diagnosis often begins by discussing these symptoms with a healthcare provider. In more serious cases, or when prescription medication is not effective, a physical exam or additional tests may be recommended to uncover any underlying conditions contributing to the ED.
The Journal of Sexual Medicine identifies several classes of drugs that can contribute to ED, including:
Oral ED treatments (pills, tablets, etc.) typically work by blocking the PDE5 enzyme to increase blood flow to the penis. It's important to note that these medications do not create sexual desire—they simply aid in the physical response needed to get and maintain an erection.
💡Pro Tip: Enhancing sexual desire
Most ED medications help with physical performance, but they can’t increase desire—it’s a complex issue that goes beyond medicine. For a proven fix, simple habits can make a real difference: eating well • staying active • managing stress • sleeping well • connecting emotionally • being open about intimacy • trying new things with partner(s).
Popular ED pills include options that enhance blood flow to the penis, providing effective relief for many men experiencing difficulty achieving an erection. Rugiet, Maximus, and Hims are popular picks for their long-lasting, fast-acting, and combination products.
Common guidelines for ED pills:
Certain blood pressure medications have been linked to ED, including beta-blockers and diuretics. Alpha-blockers, ACE inhibitors, and ARBs may be less likely to cause ED. Some research suggests the link between blood pressure medication and ED may be more psychological than physical, and that fear of potential side effects—or other unrelated health issues, can trigger ED symptoms.1
Statins are a class of drugs primarily prescribed to lower cholesterol, not as a direct treatment for ED. However, if your ED is linked to high cholesterol from conditions like cardiovascular disease, peripheral artery disease, diabetes, or high blood pressure, statins may improve erectile function when used alongside common prescription ED medications.11
Nitric oxide is a vital compound for many bodily functions, including hormone release, neutransmission, and blood vessel dialation, which is crucial for maintaining erections.3,6 Production of this compound is fuelled by amino acids like L-citrulline and L-arganine.
L-citrulline and L-arganine supplements or foods rich in L-citrulline and L-arganine (nuts, meat, watermelon, legumes, dairy products, red meat, fish and poultry) may or may not be effective in boosting sexual performance in men–the science varies.6
Testosterone levels naturally decrease as men age, but lifestyle factors may help slow this decline.
A balanced diet rich in leafy greens, fatty fish, healthy oils, and adequate zinc intake can support testosterone production. Regular exercise, weight lifting, managing stress, getting enough sleep, and maintaining vitamin D levels are also key.2,7
While some herbal supplements claim to boost testosterone, the science is inconclusive.
Testosterone replacement therapy (TRT) is the only FDA-approved treatment for low testosterone. It must be prescribed by doctors and is administered via injections, gels, patches, implants, or oral methods. (Only 0.9% to 2.9% of U.S. men are prescribed TRT.)10
Some vitamins and supplements may help alleviate ED symptoms, but they are not as effective as prescription medications.8 Vitamins that support male sexual health can include B3, B9, B12, C, and D.
A balanced diet and sun exposure typically provides sufficient vitamins and taking excessive amounts can be harmful, interact with medications, or cause side effects, unless advised by a doctor.
Eroxon, the only FDA-authorized ED gel, is available without a prescription and works by stimulating nerves through cooling and heating effects. Some men report mild skin irritation, discomfort at the application site, painful erections–And, there’s of course the possibility that any negative effects of creams can affect your partner(s) upon physical contact.
Though the effects are usually mild and temporary, ED meds can cause headaches, flushing, indigestion, nasal congestion, dizziness, and mild vision disturbances.
Side effects vary from person to person, and the best ED medication without side effects will depend on your unique health profile. Low-dose pills can be an effective way to manage symptoms with potentially fewer drawbacks.
A vacuum pump for erectile dysfunction draws blood into the penis via a hand- or batter-operated pump, and a constriction ring is placed at the base of the penis to maintain the erection. Results are often temporary, requiring consistent and immediate use before sexual activity. The ring should be removed after about 30 minutes to avoid potential side effects.
Vacuum pumps for ED can be purchased online without a prescription, or a doctor can recommend specific models and brands.
Shockwave therapy machines for erectile dysfunction use low-intensity sound waves to stimulate the growth of new blood vessels in the penis. It designed for men with more persistent cases of ED or men who don’t respond to oral ED medication.
The procedure requires specialized equipment and is typically performed in a medical office or clinic. At-home devices are available, but their effectiveness and safety may not be as well-supported.
ED injections are self-administered at home with a small needle before each sexual encounter. While they work quickly and reliably, these injections are typically reserved for men who don’t respond to oral ED medications.
There are no FDA-approved over-the-counter (OTC) oral medications for ED. While various supplements are marketed as ‘miracle cures’ for ED, their side effects can range from mild to severe depending on your health and medical history.
Improving lifestyle habits—such as exercising regularly, maintaining a healthy diet, reducing alcohol consumption, and quitting smoking—can potentially improve ED symptoms and have positive effects on sexual performance.4
Recent statistics on ED suggest that reversibility is possible for many men. According to newer research, around 32% of men experience remission from ED within five years, particularly with the right treatments.
While this varies depending on the underlying cause, lifestyle improvements, psychological interventions (such as therapy for performance anxiety), and medications often play a significant role in managing or reversing the condition.
Common side effects of ED medications include:
Rarely, more serious side effects or prolonged symptoms that require immediate medical attention can occur. ED medications can interact with certain drugs, particularly those used to treat heart conditions. It’s important to follow a healthcare provider’s guidance.
Take ED medication as prescribed by a doctor, and don’t exceed the recommended dose. If ED persists or significantly impacts quality of life, it's important to seek medical advice. Early consultation with a healthcare provider can help manage both the ED and any related health concerns.
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Rugiet
Rugiet Ready delivers fast, powerful results by targeting both physical performance and mental arousal. With a unique blend of three active ingredients in a quick-dissolving dose, it’s designed to work in minutes—ready whenever the moment strikes.
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hims
Hims offers an affordable, hassle-free way to access prescription ED medication—no virtual visit required. Choose from brand-name and generic options, along with Hims’ own exclusive formulations. The process is private and convenient, with discreet packaging and quick home delivery or pharmacy pickup.
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